MHP Xpel Review: Ingredients, Cost & Does It Work?

When we heard a water-loss supplement was being marketed for weight loss, we knew our research team would have plenty to dig into. There’s no inherent reason an herbal diuretic should help with genuine weight loss, so we took a close look at the actual formula.

Our researchers examined the ingredients, potential side effects, the company behind the product, and what the science actually says. Here’s the bottom line.

What Is MHP Xpel?

MHP Xpel is a maximum-strength diuretic water pill made from all-natural ingredients. Even though it’s listed in the weight-loss section of the official website, it’s worth looking at the underlying research first. Uva-ursi extract has been shown to be an effective diuretic, per Trials. Juniper has a long history of traditional use for various conditions, including as a diuretic, according to Heliyon. And dandelion extract has been confirmed as an effective diuretic in more recent research, per the Journal of the Society for Biomedical Diabetes Research.

Who Makes MHP Xpel?

Maximum Human Performance (MHP), founded in 1997, has grown into a globally recognized brand serving athletes, though its products are broadly usable by anyone. Other MHP products include Dark Matter, Probolic-SR, T-Bomb 3Xtreme, Up Your Mass XXXL, Anadrox 2-in-1, Activite Sport, and Secretagogue One.

Company Behind MHP Xpel

MHP is based in New Jersey, manufacturing all products domestically from both U.S. and international ingredients. Address: 165 Clinton Rd, West Caldwell, NJ 07006. Email: customerservice@mhpstrong.com. Phone: (888) 783-8844. Hours: 9am–4pm EST.

Return Policy

Items can be returned for any reason within 30 days of purchase, with the ship date counting as the purchase date for online and catalog orders. Unopened items receive a full refund in the original payment method; opened items receive merchandise credit.

MHP Xpel Claims

As a water pill, Xpel is designed to increase water loss, meaning more frequent bathroom trips and, potentially, increased thirst. It’s important to stay well hydrated while using it, since the goal is eliminating excess water retention, not all fluid in the body. Marketed benefits include increased water loss, reduced water retention, improved muscle definition, reduced bloating, weight-loss support, electrolyte supplementation, reduced cramping, optimized muscle performance, and suitability for both men and women.

MHP Xpel Ingredients

The formula includes fairly standard water-pill ingredients: vitamin B6, calcium, magnesium, potassium, uva ursi leaf, juniper berry, dandelion extract, horsetail extract, hydrangea root, buchu leaf, couch grass rhizome, cornsilk stylus, green tea leaf extract, and guarana seed extract. One genuine plus: the inclusion of electrolytes to help replace what’s lost through increased urination.

A Closer Look at the Ingredients

Most of these ingredients are reasonably likely to increase urination as claimed, which typically means some temporary weight loss — though that doesn’t necessarily mean using a water pill for weight purposes is a good idea. Diuretics are meant for temporary, targeted use, not sustained weight management.

Calcium, Magnesium, Potassium — Three electrolytes commonly depleted by water pills; their inclusion here is meant to offset that loss.

Uva Ursi Leaf — Research in Trials shows uva ursi supports women’s urinary health specifically (the study population); it’s plausible a similar effect occurs in men, though that hasn’t been separately confirmed. It’s also used traditionally as a diuretic.

Juniper Berry — Shows antibacterial and antifungal properties per Acta Pharmaceutica, and a test-tube study on human cells found it reduced cellular inflammation, according to Cogent Medicine.

Dandelion Extract — Human research, including a study in the Journal of Alternative and Complementary Medicine, confirms dandelion promotes water loss through increased urination.

Horsetail Extract — A small study in Evidence-based Complementary and Alternative Medicine showed increased urination with horsetail use, though no other significant research confirms the effect.

Hydrangea Root — No research currently supports a specific health benefit.

Buchu Leaf — A single study in the Scottish Medical Journal references buchu leaf’s traditional use as a diuretic.

Green Tea Leaf Extract — No direct link to urinary health or water loss, but well documented for broader benefits — a study in Medicine and Science in Sports and Exercise found green tea supplementation helped “improve performance and delay muscle fatigue,” with additional research in Nutrition Research, the Journal of Complementary and Integrative Medicine, and Critical Reviews in Food Science and Nutrition confirming strong antioxidant support.

Guarana Seed Extract — No documented connection to water loss or urinary health, but a known energy booster, per PLoS One — likely included here to help offset the fatigue that can accompany fluid loss.

How to Use and MHP Xpel Dosage

The label instructs: “Take 4 capsules with 16 fl. oz. of water twice daily — once in the morning and once in the afternoon. Drink at least 6-8 glasses of water daily. Do not exceed the recommended dosage.”

MHP Xpel Cost and Where to Buy

Widely available through trusted retailers: GNC ($23.99), Amazon ($16.22), Vitamin Shoppe ($19.42), and the official website ($24.50).

MHP Xpel Side Effects

Like most diuretics, MHP Xpel carries a well-documented list of potential side effects: increased urination, water weight loss, constipation, diarrhea, abdominal cramping, and electrolyte imbalance. The product also received a warning from the Philippines’ Food and Drug Administration over insufficient quality and safety testing.

Pros and Cons

Pros: Genuinely promotes water loss, includes electrolytes to help offset what’s lost, and delivers noticeable (if temporary) weight loss.

Cons: Weight loss from water pills doesn’t last, long-term diuretic use can cause health problems, and electrolyte imbalance is a serious risk worth taking seriously.

The Bottom Line on MHP Xpel

MHP Xpel does what a water pill is designed to do — shed excess water weight temporarily. What it won’t do is deliver lasting, meaningful weight loss. Anyone focused on genuine, sustainable results is better served looking elsewhere, since real progress ultimately comes down to consistent diet and exercise habits rather than short-term water manipulation.

Explore more Diet Supplement reviews and guides on our site.

For general guidance on healthy weight management, see the resources available from the CDC.